OS9 antibody

Catalog No. ABIN6292774

Product Details anti-OS9 Antibody

Target: OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OS9 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human OS9

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Ubiquitously expressed, Found as well in all tumor cell lines analyzed, amplified in sarcomas, Highly expressed in osteosarcoma SJSA-1 and rhabdomyosarcoma Rh30 cell lines, Isoform 2 is the major isoform detected in all cell types examined

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for OS9

Target: OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))

Alternative Name: OS9 (OS9 Products)

Synonyms: OS-9 antibody, zgc:153838 antibody, 4632413K17Rik antibody, AU022351 antibody, Os-9 antibody, ERLEC2 antibody, OS9, endoplasmic reticulum lectin antibody, osteosarcoma amplified 9, endoplasmic reticulum lectin antibody, amplified in osteosarcoma antibody, OS9 antibody, os9 antibody, Os9 antibody

Background: This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 75.562 kDa

Gene ID: 10956

UniProt: Q13438

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome