MIIP antibody

Catalog No. ABIN6293240

Product Details anti-MIIP Antibody

Target: MIIP (Migration and Invasion Inhibitory Protein (MIIP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIIP antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human MIIP

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Ubiquitous, Isoform 1 is expressed in brain but underexpressed in glioma tissues, at protein level, Isoform 2 is not detected in normal organs, but is expressed in gliomas with increasing levels with glioma progression, On the contrary, at protein level, isoform 2 is not detected in gliomas, suggesting that this isoform is unstable in glioma cells

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for MIIP

Target: MIIP (Migration and Invasion Inhibitory Protein (MIIP))

Alternative Name: MIIP (MIIP Products)

Synonyms: IIP45 antibody, AA553001 antibody, AI853621 antibody, D4Wsu114e antibody, Iip45 antibody, migration and invasion inhibitory protein antibody, MIIP antibody, Miip antibody

Background: This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers.

Molecular Weight: 42.824 kDa

Gene ID: 60672

UniProt: Q5JXC2