P2RY12 antibody

Catalog No. ABIN6293326

Product Details anti-P2RY12 Antibody

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY12 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human P2RY12

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highly expressed in the platelets, lower levels in the brain, Lowest levels in the lung, appendix, pituitary and adrenal gland, Expressed in the spinal cord and in the fetal brain

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for P2RY12

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Alternative Name: P2RY12 (P2RY12 Products)

Synonyms: 2900079B22Rik antibody, 4921504D23Rik antibody, P2Y12 antibody, ADPG-R antibody, BDPLT8 antibody, HORK3 antibody, P2T(AC) antibody, P2Y(12)R antibody, P2Y(AC) antibody, P2Y(ADP) antibody, P2Y(cyc) antibody, SP1999 antibody, P2y12 antibody, purinergic receptor P2Y, G-protein coupled 12 antibody, purinergic receptor P2Y12 antibody, P2ry12 antibody, P2RY12 antibody

Background: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Molecular Weight: 39.439 kDa

Gene ID: 64805

UniProt: Q9H244