MKKS antibody

Catalog No. ABIN6293382

Product Details anti-MKKS Antibody

Target: MKKS (McKusick-Kaufman Syndrome (MKKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKKS antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human MKKS

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Widely expressed in adult and fetal tissues

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for MKKS

Target: MKKS (McKusick-Kaufman Syndrome (MKKS))

Alternative Name: MKKS (MKKS Products)

Synonyms: bbs6 antibody, zgc:55608 antibody, MKKS antibody, kms antibody, mks antibody, hmcs antibody, DKFZp459L0833 antibody, BBS6 antibody, HMCS antibody, KMS antibody, MKS antibody, 1300013E18Rik antibody, AI463362 antibody, AI957237 antibody, Bbs6 antibody, McKusick-Kaufman syndrome antibody, Mkks antibody, mkks antibody, MKKS antibody

Background: This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight: 62.342 kDa

Gene ID: 8195

UniProt: Q9NPJ1

Pathways: Sensory Perception of Sound