WNK3 antibody

Catalog No. ABIN6293469

Product Details anti-WNK3 Antibody

Target: WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNK3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human WNK3

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Expressed in brain, lung, kidney, liver and pancreas, and in fetal tissues including placenta, fetal brain, lung and kidney, Very low levels of expression were also detected in fetal heart, thymus, liver and spleen, Isoform 1 is brain-specific, Isoform 3 is kidney-specific

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for WNK3

Target: WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))

Alternative Name: WNK3 (WNK3 Products)

Synonyms: fc63h12 antibody, PRKWNK3 antibody, Prkwnk3 antibody, Wnk3-ps antibody, RGD1563131 antibody, wu:fc63h12 antibody, WNK lysine deficient protein kinase 3 antibody, wu:fc63h12 antibody, LOC100363278 antibody, WNK3 antibody, Wnk3 antibody

Background: This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.

Molecular Weight: 198.416 kDa

Gene ID: 65267

UniProt: Q9BYP7