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WNK3 Products

(WNK Lysine Deficient Protein Kinase 3 (WNK3))

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This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].

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Featured WNK3 Categories

WNK3 Antibodies

High quality antibodies with extensive validation data.

Recommended WNK3 Antibodies

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Reactivity Human, Rat
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Cat. No. ABIN675713
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Cat. No. ABIN6150236
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Cat. No. ABIN7271382
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Recommended WNK3 Proteins

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Reactivity Human
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Cat. No. ABIN5569660
Quantity 5 μg
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1325352
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Latest Publications for our WNK3 products

Haas, Cuddapah, Watkins, Rohn, Dy, Sontheimer: "With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume." in: American journal of physiology. Cell physiology, Vol. 301, Issue 5, pp. C1150-60, (2011) (PubMed).

Zhang, Na, Peng: "WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway." in: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1472-84, (2008) (PubMed).

Rinehart, Kahle, de Los Heros, Vazquez, Meade, Wilson, Hebert, Gimenez, Gamba, Lifton: "WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 46, pp. 16777-82, (2005) (PubMed).

Veríssimo, Jordan: "WNK kinases, a novel protein kinase subfamily in multi-cellular organisms." in: Oncogene, Vol. 20, Issue 39, pp. 5562-9, (2001) (PubMed).

Nagase, Kikuno, Nakayama, Hirosawa, Ohara: "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 4, pp. 273-81, (2000) (PubMed).

Synonyms and alternative names related to WNK3

wu:fc63h12 (wu:fc63h12), WNK lysine deficient protein kinase 3 (LOC100363278), WNK lysine deficient protein kinase 3 (WNK3), WNK lysine deficient protein kinase 3 (Wnk3), fc63h12, PRKWNK3, Prkwnk3, RGD1563131, Wnk3-ps

Protein level used designations for WNK3

  • wu:fc63h12
  • WNK lysine deficient protein kinase 3
  • protein kinase with no lysine 3
  • serine/threonine-protein kinase WNK3
  • WNK lysine deficient protein kinase 3, pseudogene
  • protein kinase lysine-deficient 3
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