PUM1 antibody

Catalog No. ABIN6293483

Product Details anti-PUM1 Antibody

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUM1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human pum1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in brain, heart, kidney, muscle, intestine and stomach, Not expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen, Expressed in all fetal tissues tested

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for PUM1

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Alternative Name: PUM1 (PUM1 Products)

Synonyms: fb96a03 antibody, pumilio1 antibody, si:ch211-285e16.1 antibody, wu:fb96a03 antibody, wu:fb96a08 antibody, zgc:63671 antibody, PUM1 antibody, DKFZp459K0627 antibody, AA517475 antibody, Pumm antibody, mKIAA0099 antibody, HSPUM antibody, PUMH antibody, PUMH1 antibody, PUML1 antibody, pumilio RNA-binding family member 1 antibody, pumilio RNA binding family member 1 antibody, pum1 antibody, PUM1 antibody, Pum1 antibody

Background: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 126.473 kDa

Gene ID: 9698

UniProt: Q14671