TBL1XR1 antibody

Catalog No. ABIN6293614

Product Details anti-TBL1XR1 Antibody

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1XR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human TBL1XR1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IF 1:50 - 1:200

Comment:

Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for TBL1XR1

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Alternative Name: TBL1XR1 (TBL1XR1 Products)

Synonyms: tbl1xr1 antibody, zgc:63617 antibody, c21 antibody, dc42 antibody, ira1 antibody, TBLR1 antibody, TBL1XR1 antibody, wu:fc46g07 antibody, zgc:110312 antibody, C21 antibody, DC42 antibody, IRA1 antibody, RGD1560053 antibody, 8030499H02Rik antibody, A630076E03Rik antibody, AW539987 antibody, C230089I12Rik antibody, Ira1 antibody, transducin (beta)-like 1 X-linked receptor 1b antibody, transducin (beta)-like 1 X-linked receptor 1 antibody, transducin (beta)-like 1 X-linked receptor 1a antibody, transducin beta like 1 X-linked receptor 1 antibody, transducin (beta)-like 1X-linked receptor 1 antibody, tbl1xr1b antibody, tbl1xr1 antibody, tbl1xr1a antibody, TBL1XR1 antibody, Tbl1xr1 antibody

Background: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.

Molecular Weight: 55.595 kDa

Gene ID: 79718

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha