BSCL2 antibody

Catalog No. ABIN6293870

The Rabbit Polyclonal anti-BSCL2 antibody has been validated for WB. It is suitable to detect BSCL2 in samples from Mouse and Rat.

Quick Overview for BSCL2 antibody (ABIN6293870)

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSCL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BSCL2 Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human BSCL2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level), Highly expressed in brain, testis and adipose tissue

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Alternative Name: BSCL2

Background: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).

Molecular Weight: 44.392 kDa

Gene ID: 26580

UniProt: Q96G97