NHP2 antibody

Catalog No. ABIN6293995

Product Details anti-NHP2 Antibody

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human NHP2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in brain, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus, Also expressed at lower levels in the liver

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for NHP2

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Alternative Name: NHP2 (NHP2 Products)

Synonyms: DKCB2 antibody, NHP2P antibody, NOLA2 antibody, 2410130M07Rik antibody, D11Ertd175e antibody, Nola2 antibody, NHP2 ribonucleoprotein antibody, NHP2 antibody, Nhp2 antibody

Background: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

Molecular Weight: 17.201 kDa

Gene ID: 55651

UniProt: Q9NX24

Pathways: Telomere Maintenance