STEAP2 antibody (Center)

Catalog No. ABIN6295251

The Rabbit Polyclonal anti-STEAP2 antibody (ABIN6295251) specifically detects STEAP2. The antibody is reactive with Human and Mouse samples.

Quick Overview for STEAP2 antibody (Center) (ABIN6295251)

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP2 antibody is un-conjugated

Application: Please inquire

Product Details anti-STEAP2 Antibody

Binding Specificity: AA 226-253, Center

Purpose: Rabbit Anti-STEA2 (Center) Antibody

Immunogen: This STEA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human STEA2.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Alternative Name: STEA2

Background:

Target Description: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Symbol: STEAP2

Gene ID: 261729

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis