STEAP2 antibody (AA 455-467)

Catalog No. ABIN783247

This Rabbit Polyclonal antibody specifically detects STEAP2 in IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for STEAP2 antibody (AA 455-467) (ABIN783247)

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-STEAP2 Antibody

Binding Specificity: AA 455-467

Specificity: This antibody reacts to Six Transmembrane Epithelial Antigen Of The Prostate 2 (STEAP2).

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide residues 455-467 ISRKLKRIKKGWEKSQ of the 56 kD human STEAP2. Genename: STEAP2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Alternative Name: STEAP2 / STAMP1

Background: Stamp1/Steap2 is highly expressed in prostate. It is localized to the Golgi complex, predominantly to the trans-Golgi network and to the plasma membrane. It is thought to play and important role in normal prostate and in prostate cancer progression as it showed increased expression in androgen-independent prostate cancer xenograftsSynonyms: IPCA-1, IPCA1, Metalloreductase STEAP2, PCANAP1, PUMPCn, Prostate cancer-associated protein 1, Protein upregulated in metastatic prostate cancer, STEAP-2, STMP, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1

Gene ID: 261729

NCBI Accession: NP_001035755

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis