STAT6 antibody (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced) (Biotin)

Details for Product anti-STAT6 Antibody No. ABIN6297842
Antigen
  • D12S1644
  • IL-4-STAT
  • STAT6B
  • STAT6C
  • signal transducer and activator of transcription 6
  • signal transducer and activator of transcription 6-like
  • STAT6
  • Stat6
  • LOC100859543
Reactivity
Human
324
136
114
19
18
14
14
13
8
6
3
2
1
1
Host
Rabbit
272
58
6
1
Clonality
Polyclonal
Conjugate
This STAT6 antibody is conjugated to Biotin
10
8
6
6
6
6
6
6
5
5
5
2
2
2
2
2
2
1
Application
ELISA
240
147
102
44
43
28
26
22
17
8
4
4
4
2
2
1
Options
Purpose Rabbit anti-Human Phosphorylated STAT6 Antibody [+Biotin],
Immunogen This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others STAT6 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Signal transducer and activator of transcription 6 (STAT6 Antibody Abstract)
Background

Target Description: STAT6  is a human  gene. The  protein  encoded by this gene is a member of the  STAT family  of  transcription factors.In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.Phospho-STAT6-PY is the phosphorylated form of STAT6 protein.

Gene Symbol: STAT6

Gene ID 6778
UniProt P42226
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Application Notes ELISA (recommended work dilution= 1:8,000)
Restrictions For Research Use only
Reconstitution Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.
Storage 4 °C,-20 °C,-80 °C
Storage Comment -20°C
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