MUSK antibody

Catalog No. ABIN6297871

This Rabbit Polyclonal antibody specifically detects MUSK in . It exhibits reactivity toward Human and Mouse.

Quick Overview for MUSK antibody (ABIN6297871)

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUSK antibody is un-conjugated

Application: Please inquire

Product Details anti-MUSK Antibody

Purpose: Rabbit Anti-MUSK Antibody

Immunogen: This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MUSK

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Alternative Name: MUSK

Background:

Target Description: MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.

Gene Symbol: MUSK

Gene ID: 4593

UniProt: O15146

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development