NR4A1 antibody (Middle Region)
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- Target See all NR4A1 Antibodies
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR4A1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- NR4 A1 antibody was raised against the middle region of NR4 1
- Purification
- Affinity purified
- Immunogen
- NR4 A1 antibody was raised using the middle region of NR4 1 corresponding to a region with amino acids FQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHL
- Top Product
- Discover our top product NR4A1 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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NR4A1 Blocking Peptide, catalog no. 33R-3032, is also available for use as a blocking control in assays to test for specificity of this NR4A1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NR0 1 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
- Alternative Name
- NR4A1 (NR4A1 Products)
- Synonyms
- GFRP1 antibody, HMR antibody, N10 antibody, NAK-1 antibody, NGFIB antibody, NP10 antibody, NUR77 antibody, TR3 antibody, NGFI-B antibody, Gfrp antibody, Hbr-1 antibody, Hbr1 antibody, Hmr antibody, TIS1 antibody, nur77 antibody, Ngfi-b antibody, Nur77 antibody, nuclear receptor subfamily 4 group A member 1 antibody, nuclear receptor subfamily 4, group A, member 1 antibody, NR4A1 antibody, Nr4a1 antibody
- Background
- NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- Molecular Weight
- 64 kDa (MW of target protein)
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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