Band 3/AE1 antibody
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- Target See all Band 3/AE1 (SLC4A1) Antibodies
- Band 3/AE1 (SLC4A1) (Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Band 3/AE1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purified
- Immunogen
- SLC4 A1 antibody was raised using a synthetic peptide corresponding to a region with amino acids PSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGR
- Top Product
- Discover our top product SLC4A1 Primary Antibody
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- Application Notes
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WB: 0.1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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SLC4A1 Blocking Peptide, catalog no. 33R-7368, is also available for use as a blocking control in assays to test for specificity of this SLC4A1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SLC0 1 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- Band 3/AE1 (SLC4A1) (Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1))
- Alternative Name
- SLC4A1 (SLC4A1 Products)
- Synonyms
- AE1 antibody, BND3 antibody, CD233 antibody, DI antibody, EMPB3 antibody, EPB3 antibody, FR antibody, RTA1A antibody, SW antibody, WD antibody, WD1 antibody, WR antibody, Ae1 antibody, Empb3 antibody, l11Jus51 antibody, ae1 antibody, band3 antibody, MGC152771 antibody, zgc:111889 antibody, zgc:152771 antibody, si:dz180g5.1 antibody, LOC100136769 antibody, slc4a1 antibody, wd1 antibody, bnd3 antibody, epb3 antibody, cd233 antibody, empb3 antibody, rta1a antibody, MGC80391 antibody, SLC4A1 antibody, BB3 antibody, EAT antibody, solute carrier family 4 member 1 (Diego blood group) antibody, solute carrier family 4 (anion exchanger), member 1 antibody, solute carrier family 4 (anion exchanger), member 1a (Diego blood group) antibody, Band 3 antibody, erythrocyte membrane protein band 4.1 like 3 antibody, solute carrier family 4 member 1 (Diego blood group) L homeolog antibody, solute carrier family 4 member 1 antibody, SLC4A1 antibody, Slc4a1 antibody, slc4a1a antibody, LOC100136769 antibody, EPB41L3 antibody, slc4a1.L antibody, slc4a1 antibody
- Background
- The CD233 gene is located on chromosome 17q21-q22 and is part of the anion exchanger (AE) family. CD233 is expressed in the erythrocyte plasma membrane where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40 kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. CD233 associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of CD233.
- Molecular Weight
- 102 kDa (MW of target protein)
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