TGM1 antibody

Catalog No. ABIN632050

Product Details anti-TGM1 Antibody

Target: TGM1 (Transglutaminase 1, Keratinocyte (TGM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGM1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purified

Immunogen: Transglutaminase 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids RGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSS

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Transglutaminase 1 Blocking Peptide, catalog no. 33R-7943, is also available for use as a blocking control in assays to test for specificity of this Transglutaminase 1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TGM1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for TGM1

Target: TGM1 (Transglutaminase 1, Keratinocyte (TGM1))

Alternative Name: Transglutaminase 1 (TGM1 Products)

Synonyms: TGM1 antibody, ARCI1 antibody, ICR2 antibody, KTG antibody, LI antibody, LI1 antibody, TGASE antibody, TGK antibody, 2310004J08Rik antibody, Tgase1 antibody, transglutaminase 1 antibody, transglutaminase 1, K polypeptide antibody, Tgm1 antibody, TGM1 antibody

Background: TGM1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).

Molecular Weight: 90 kDa (MW of target protein)