BRISC and BRCA1 A Complex Member 1 (BABAM1) (N-Term) antibody
Quick Overview for BRISC and BRCA1 A Complex Member 1 (BABAM1) (N-Term) antibody (ABIN632802)
Target
See all BRISC and BRCA1 A Complex Member 1 (BABAM1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- N-Term
-
Specificity
- C19 ORF62 antibody was raised against the N terminal Of C19 rf62
-
Purification
- Affinity purified
-
Immunogen
- C19 ORF62 antibody was raised using the N terminal Of C19 rf62 corresponding to a region with amino acids DRAVGAQASVGSRSEGEGEAASADDGSLNTSGAGPKSWQVPPPAPEVQIR
-
-
-
-
Application Notes
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
-
C19ORF62 Blocking Peptide, (ABIN937526), is also available for use as a blocking control in assays to test for specificity of this C19ORF62 antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of C10 RF62 antibody in PBS
-
Concentration
- Lot specific
-
Buffer
- PBS
-
Handling Advice
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- BRISC and BRCA1 A Complex Member 1 (BABAM1)
-
Alternative Name
- C19ORF62
-
Background
- C19orf62 is a component of the BRCA1-A complex, a complex that specifically recognises 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).
-
Molecular Weight
- 36 kDa (MW of target protein)
-
Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
-