KPNA2 antibody
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- Target See all KPNA2 Antibodies
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KPNA2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purified
- Immunogen
- Karyopherin Alpha 2 antibody was raised using a synthetic peptide corresponding to a region with amino acids GTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQ
- Top Product
- Discover our top product KPNA2 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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Karyopherin Alpha 2 Blocking Peptide, catalog no. 33R-3602, is also available for use as a blocking control in assays to test for specificity of this Karyopherin Alpha 2 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KPNA2 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
- Alternative Name
- Karyopherin alpha 2 (KPNA2 Products)
- Synonyms
- IPOA1 antibody, QIP2 antibody, RCH1 antibody, SRP1alpha antibody, ima2 antibody, importin antibody, 2410044B12Rik antibody, PTAC58 antibody, Rch1 antibody, ipoa1 antibody, kpna2 antibody, qip2 antibody, rch1 antibody, srp1alpha antibody, hm:zeh0389 antibody, hm:zeh0389r antibody, zgc:113902 antibody, zgc:86945 antibody, karyopherin subunit alpha 2 antibody, importin subunit alpha-2 antibody, Importin subunit alpha-2 antibody, karyopherin (importin) alpha 2 antibody, karyopherin alpha-2 subunit like L homeolog antibody, karyopherin alpha 2 (RAG cohort 1, importin alpha 1) antibody, KPNA2 antibody, EDI_246290 antibody, EDI_335040 antibody, ima2 antibody, Kpna2 antibody, kpna2.L antibody, kpna2 antibody
- Background
- Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins.
- Molecular Weight
- 58 kDa (MW of target protein)
- Pathways
- M Phase, Protein targeting to Nucleus
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