Patched 2 antibody (AA 226-235)

Catalog No. ABIN636197

Product Details anti-Patched 2 Antibody

Target: Patched 2 (PTCH2)

Binding Specificity: AA 226-235

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Patched 2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Affinity chromatography purified

Immunogen: PTCH2 antibody was raised in rabbit using AA 226-235 [GPFASLEGFR] of the human PTCH2 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Patched 2

Target: Patched 2 (PTCH2)

Alternative Name: PTCH2 (PTCH2 Products)

Synonyms: PTC2 antibody, ptc2 antibody, Ptch1 antibody, ptc-2 antibody, xptc-2 antibody, xptch-2 antibody, patched-2 antibody, ptch2 antibody, ptc-1 antibody, ptc1 antibody, ptch1 antibody, patched 2 antibody, patched 2 S homeolog antibody, patched 2 L homeolog antibody, PTCH2 antibody, Ptch2 antibody, ptch2.S antibody, ptch2.L antibody, ptch2 antibody

Background: Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

Pathways: Hedgehog Signaling