NOV antibody

Catalog No. ABIN636676

Product Details anti-NOV Antibody

Target: NOV (Nephroblastoma Overexpressed (NOV))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOV antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogen: NOV antibody was raised in rabbit using highly pure recombinant human NOV as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for NOV

Target: NOV (Nephroblastoma Overexpressed (NOV))

Alternative Name: NOV (NOV Products)

Synonyms: CCN3 antibody, IBP-9 antibody, IGFBP-9 antibody, IGFBP9 antibody, NOVh antibody, nov-A antibody, xnov antibody, NovH antibody, C130088N23Rik antibody, nephroblastoma overexpressed antibody, nephroblastoma overexpressed L homeolog antibody, nephroblastoma overexpressed gene antibody, NOV antibody, nov.L antibody, Nov antibody

Background: NOV is a member of the CCN family of secreted cysteine rich regulatory proteins. The full length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm’s tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorgenicity and proliferation is correlated with decreased NOV expression.

Molecular Weight: 36.2 kDa (predicted detection band MW)

Pathways: Smooth Muscle Cell Migration, Growth Factor Binding