(1 reference)-
- Target See all Dinitrophenol (DNP) products
- Dinitrophenol (DNP)
-
Host
- Goat
-
Clonality
- Polyclonal
-
Conjugate
- This Dinitrophenol antibody is un-conjugated
-
Application
- ELISA, Western Blotting (WB)
- Immunogen
- Dinitrophenol antibody was raised in goat using dinitrophenol-modified protein as the immunogen.
-
-
- Application Notes
-
ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Supplied as liquid whole serum without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
-
-
: "Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment." in: BMC neuroscience, Vol. 21, Issue 1, pp. 4, (2020) (PubMed).
-
: "Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment." in: BMC neuroscience, Vol. 21, Issue 1, pp. 4, (2020) (PubMed).
-
- Target
- Dinitrophenol (DNP)
- Alternative Name
- DNP (DNP Products)
- Target Type
- Chemical
- Background
- Tissues are continually exposed to reactive oxygen species (ROS) that are produced in tissues from metabolism processes or the inflammatory response of leukocytes or macrophages. It is estimated that as much as 1 % of consumed oxygen may be converted to ROS, which can cause damage to various cellular components. Proteins are one of the cellular components most vulnerable to oxidative damage by ROS, which results in an increase in protein carbonyl content. This oxidative modification of proteins can lead to cross-linking, peptide fragmentation, modified residues and the conversion of one amino group to another. If sufficient protein damage accumulates, cell death will occur.
-
You are here:
