GZMB antibody

Catalog No. ABIN640668

The Mouse Monoclonal anti-GZMB antibody (ABIN640668) specifically detects GZMB in ELISA, FACS, IF, IP and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for GZMB antibody (ABIN640668)

Target: GZMB (Granzyme B (GZMB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMB antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GZMB Antibody

Purpose: Mouse Anti-Human Granzyme B

Specificity: DS-MB-01406 recognises the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. This antibody has been reported to function as a capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated DS-MB-00405 as detection reagent.

Cross-Reactivity: Chimpanzee, Monkey, Rhesus Monkey

Characteristics: Phosphorylation/Apoptosis/Signal Transduction/Regulation

Purification: Purified

Immunogen: Purified human Granzyme B

Isotype: IgG1

Application Details

Application Notes: Immunohistology - Frozen, ELISA (dilution: 1/10 , 1/100), Flow Cytometry, Immunofluorescence, Immunoprecipitation

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: TRIS buffered saline

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for GZMB

Target: GZMB (Granzyme B (GZMB))

Alternative Name: Granzyme B

Pathways: Apoptosis, Caspase Cascade in Apoptosis