TrkA-pY791 (AA 769-796) antibody
Reactivity: Human, Mouse
FACS, WB, IHC (p)
Host: Rabbit
Polyclonal
RB16572
unconjugated
-
- Target
- TrkA-pY791
- Binding Specificity
- AA 769-796
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TrkA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 769-796 amino acids from human TrkA.
- Clone
- RB16572
- Isotype
- Ig Fraction
-
- Application Notes
- WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:10~50. FC: 1:25
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
-
- Target
- TrkA-pY791
- Background
- TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
- Molecular Weight
- 87497
- Gene ID
- 4914
- NCBI Accession
- NP_001007793, NP_001012331, NP_002520
- UniProt
- P04629
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