Calpastatin antibody (CAST)

Details for Product anti-CAST Antibody No. ABIN6566472
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
86
25
22
4
Host
Rabbit
67
22
3
Clonality
Polyclonal
Conjugate
This Calpastatin antibody is un-conjugated
6
4
4
3
3
3
3
3
3
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
61
35
26
19
13
13
10
7
4
2
2
1
1
Options
Immunogen A synthetic peptide of human CAST
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name CAST (CAST Antibody Abstract)
Background

Synonyms: BS 17,Calpain inhibitor,Calpastatin,Cast,Heart type calpastatin,ICAL,MGC9402,Sperm BS 17 component,Sperm BS-17 component

Background: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight

Observed_MW: 124kDa

Calculated_MW: 63kDa/71- 84kDa

Gene ID 831
UniProt P20810
Application Notes WB 1:200 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Calpastatin (CAST) antibody (ABIN6566472) Immunohistochemistry of paraffin-embedded rat heart using CAST antibody.
Image no. 2 for anti-Calpastatin (CAST) antibody (ABIN6566472) Immunohistochemistry of paraffin-embedded human stomach using CAST antibody.
Image no. 3 for anti-Calpastatin (CAST) antibody (ABIN6566472) Western blot analysis of extracts of H460 cells, using CAST antibody.
Image no. 4 for anti-Calpastatin (CAST) antibody (ABIN6566472) Immunohistochemistry of paraffin-embedded mouse brain using CAST antibody.