NUMA1 antibody
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- Target See all NUMA1 Antibodies
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NUMA1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human NUMA1
- Isotype
- IgG
- Top Product
- Discover our top product NUMA1 Primary Antibody
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- Application Notes
- WB 1:200 - 1:1000 IHC 1:50 - 1:100
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Alternative Name
- NUMA1 (NUMA1 Products)
- Synonyms
- NUMA antibody, 6720401E04Rik antibody, AA764025 antibody, AL022610 antibody, AU014979 antibody, NUMA1 antibody, NuMA antibody, SP-H antibody, numa antibody, numa1 antibody, nuclear mitotic apparatus protein 1 antibody, nuclear mitotic apparatus protein 1 S homeolog antibody, NUMA1 antibody, Numa1 antibody, numa1 antibody, numa1.S antibody
- Background
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Synonyms: Centrophilin stabilizes mitotic spindle in mitotic cells,NMP 22,Nuclear matrix protein 22,Nuclear mitotic apparatus protein 1,Nuclear mitotic apparatus protein,NUMA 1,NUMA,NuMA protein,NUMA1,NUMA1,SP H antigen,SP-H antigen,Structural nuclear protein
Background: This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 238kDa
Calculated_MW: 109kDa/200kDa/201kDa/236kDa/238kDa
- Gene ID
- 4926
- UniProt
- Q14980
- Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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