SNAPIN antibody

Catalog No. ABIN6566859

Product Details anti-SNAPIN Antibody

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAPIN antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human SNAPIN

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Alternative Name: SNAPIN (SNAPIN Products)

Synonyms: SNAPAP antibody, si:dkey-222b8.2 antibody, SNAPIN antibody, BLOC1S7 antibody, BLOS7 antibody, 25kDa antibody, AA407989 antibody, AV026596 antibody, Bloc1s7 antibody, Snap25bp antibody, Snapap antibody, SNAP associated protein antibody, SNAP-associated protein L homeolog antibody, SNAP-associated protein antibody, SNAPIN antibody, snapin.L antibody, snapin antibody, Snapin antibody

Background:

Synonyms: OTTHUMP00000035157,SNAP associated protein,SNAP-25-binding protein,SNAP-associated protein,SNAP25BP,SNAPAP,Snapin,SNAPN,SNARE associated protein snapin,SNARE-associated protein Snapin,Synaptosomal associated protein 25 binding protein,Synaptosomal-associated protein 25-binding protein

Background: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 15kDa

Calculated_MW: 14kDa

Gene ID: 23557

UniProt: O95295

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis