MTMR3 antibody

Catalog No. ABIN5963803

Product Details anti-MTMR3 Antibody

Target: MTMR3 (Myotubularin Related Protein 3 (MTMR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human MTMR3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTMR3

Target: MTMR3 (Myotubularin Related Protein 3 (MTMR3))

Alternative Name: MTMR3 (MTMR3 Products)

Synonyms: MGC68981 antibody, MGC143436 antibody, DKFZp459K2113 antibody, FYVE-DSP1 antibody, ZFYVE10 antibody, 1700092A20Rik antibody, AI255150 antibody, AW557713 antibody, mKIAA0371 antibody, myotubularin-related protein 3 antibody, myotubularin related protein 3 antibody, myotubularin related protein 3 L homeolog antibody, mtmr3 antibody, MTMR3 antibody, mtmr3.L antibody, Mtmr3 antibody

Background:

Synonyms: FYVE domain-containing dual specificity protein phosphatase 1,FYVE-DSP1,MTMR3,MTMR3,Myotubularin-related protein 3,Zinc finger FYVE domain-containing protein 10

Background: This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 150kDa

Calculated_MW: 129kDa/130kDa/133kDa

Gene ID: 8897

UniProt: Q13615

Pathways: Inositol Metabolic Process