SIPA1 antibody
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- Target See all SIPA1 Antibodies
- SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIPA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human SIPA1
- Isotype
- IgG
- Top Product
- Discover our top product SIPA1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
- Alternative Name
- SIPA1 (SIPA1 Products)
- Synonyms
- Spa1 antibody, SPA1 antibody, signal-induced proliferation-associated 1 antibody, Signal peptidase I (leader peptidase I) antibody, signal-induced proliferation associated gene 1 antibody, SIPA1 antibody, sipA1 antibody, Sipa1 antibody
- Background
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Synonyms: GTPase activating protein Spa 1,GTPase-activating protein Spa-1,MGC102688,MGC17037,p130 SPA-1,p130 SPA1,Signal induced proliferation associated 1,Signal induced proliferation associated gene 1,Signal induced proliferation associated protein 1,Signal-induced proliferation-associated protein 1,SIPA 1,Sipa-1,Sipa1,SIPA1,Spa1
Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
- Molecular Weight
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Observed_MW: 130kDa
Calculated_MW: 112kDa
- Gene ID
- 6494
- UniProt
- Q96FS4
- Pathways
- Response to Water Deprivation
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