KLRC1 antibody

Catalog No. ABIN6567417

Product Details anti-KLRC1 Antibody

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRC1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human KLRC1 (NP_015567.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KLRC1

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Alternative Name: KLRC1 (KLRC1 Products)

Synonyms: rNKG2A antibody, NKG2-A antibody, NKG2A antibody, KLRC1 antibody, CD159A antibody, NKG2 antibody, CD159a antibody, NKG2B antibody, killer cell lectin like receptor C1 antibody, NKG2-A/NKG2-B type II integral membrane protein-like antibody, killer cell lectin-like receptor subfamily C, member 3 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, Klrc1 antibody, KLRC1 antibody, NKG2A antibody, KLRC3 antibody

Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molecular Weight:

Observed_MW: 26kDa

Calculated_MW: 24kDa/26kDa

Gene ID: 3821

UniProt: P26715