UHRF2 antibody
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- Target See all UHRF2 Antibodies
- UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UHRF2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human UHRF2 (NP_690856.1).
- Isotype
- IgG
- Top Product
- Discover our top product UHRF2 Primary Antibody
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- Application Notes
- IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))
- Alternative Name
- UHRF2 (UHRF2 Products)
- Synonyms
- NIRF antibody, RNF107 antibody, URF2 antibody, 2310065A22Rik antibody, AI426270 antibody, AW214556 antibody, D130071B19Rik antibody, Nirf antibody, ubiquitin like with PHD and ring finger domains 2 antibody, ubiquitin-like, containing PHD and RING finger domains 2 antibody, ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog antibody, UHRF2 antibody, Uhrf2 antibody, uhrf2.L antibody
- Background
- This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
- Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 56kDa/89kDa
- Gene ID
- 115426
- UniProt
- Q96PU4
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