GRAP antibody

Catalog No. ABIN6568682

Product Details anti-GRAP Antibody

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAP antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GRAP (NP_006604.1).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GRAP

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Alternative Name: GRAP (GRAP Products)

Synonyms: 8430435N19Rik antibody, BB233594 antibody, GRAP antibody, grap antibody, zgc:110202 antibody, MGC109892 antibody, si:dkeyp-9d4.1 antibody, Grap antibody, GRB2-related adaptor protein antibody, GRB2-related adapter protein antibody, GRB2-related adaptor protein a antibody, GRB2-related adaptor protein b antibody, GRAP antibody, Grap antibody, LOC489534 antibody, grapa antibody, grapb antibody, LOC100727005 antibody

Background: GRAP,This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Molecular Weight:

Observed_MW: 36kDa

Calculated_MW: 25kDa

Gene ID: 10750

UniProt: Q13588