ADRA2A antibody

Catalog No. ABIN6569361

Product Details anti-ADRA2A Antibody

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA2A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ADRA2A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADRA2A

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Alternative Name: ADRA2A (ADRA2A Products)

Synonyms: ADRA2A antibody, AW122659 antibody, Adra-2 antibody, Adra-2a antibody, alpha(2A)AR antibody, alpha2-C10 antibody, alpha2A antibody, alpha2A-AR antibody, ADRA2 antibody, ADRA2R antibody, ADRAR antibody, ALPHA2AAR antibody, ZNF32 antibody, CA2-47 antibody, RATRG20 antibody, RG20 antibody, PORA2AR antibody, adrenoceptor alpha 2A antibody, alpha-2A adrenergic receptor-like antibody, adrenergic receptor, alpha 2a antibody, adra2a antibody, ADRA2A antibody, LOC100414445 antibody, Adra2a antibody

Background:

Synonyms: ADA2A,ADRA2,ADRA2A,ADRA2R,ADRAR,Adrenergic alpha 2A receptor,Alpha 2 adrenergic receptor subtype C10,Alpha 2A adrenergic receptor,Alpha 2AAR subtype C10,Alpha-2 adrenergic receptor subtype C10,alpha-2-adrenergic receptor,platelet type,Alpha-2A adrenergic receptor,Alpha-2A adrenoceptor,Alpha-2A adrenoreceptor,Alpha-2AAR,ALPHA2AAR,OTTHUMP00000058849,ZNF32

Background: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

Molecular Weight:

Observed_MW: 49kDa

Calculated_MW: 48kDa

Gene ID: 150

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity