FANCI antibody

Catalog No. ABIN6569525

Product Details anti-FANCI Antibody

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCI antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human FANCI

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FANCI

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Alternative Name: FANCI (FANCI Products)

Synonyms: KIAA1794 antibody, Fanconi anemia complementation group I antibody, Fanconi anemia, complementation group I antibody, FANCI antibody, Fanci antibody

Background:

Synonyms: FANCI,FANCI gene,FANCI,Fanconi anemia group I protein,Fanconi anemia, complementation group I,FLJ10719,FLJ14658,KIAA1794,Protein FACI,Protein FANCI

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 170kDa

Calculated_MW: 27kDa/142kDa/149kDa

Gene ID: 55215

UniProt: Q9NVI1

Pathways: DNA Damage Repair