PPP1R15B antibody (C-Term)

Catalog No. ABIN657042

Product Details anti-PPP1R15B Antibody

Target: PPP1R15B (Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B))

Binding Specificity: AA 494-522, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R15B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PR15B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 494-522 amino acids from the C-terminal region of human PR15B.

Clone: RB32305

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PPP1R15B

Target: PPP1R15B (Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B))

Alternative Name: PR15B (PPP1R15B Products)

Synonyms: 1810033K10Rik antibody, AI606441 antibody, C530022L24Rik antibody, CReP antibody, CREP antibody, protein phosphatase 1, regulatory (inhibitor) subunit 15b antibody, protein phosphatase 1 regulatory subunit 15B antibody, protein phosphatase 1, regulatory subunit 15B antibody, Ppp1r15b antibody, PPP1R15B antibody

Background: PPP1R15B promotes dephosphorylation of the transcription initiation factor EIF2-alpha (EIF2S1, MIM 603907) through recruitment of protein phosphatase-1 (PP1) catalytic subunits (see MIM 176875) (Harding et al., 2009 [PubMed 19181853]).[supplied by OMIM].

Molecular Weight: 79152

NCBI Accession: NP_116222

UniProt: Q5SWA1

Pathways: ER-Nucleus Signaling