GMP Synthase antibody

Catalog No. ABIN6570561

Product Details anti-GMP Synthase Antibody

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMP Synthase antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human GMPS

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GMP Synthase

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Alternative Name: GMPS (GMPS Products)

Synonyms: GMPS antibody, AA591640 antibody, AI047208 antibody, sb:cb632 antibody, wu:fb76b01 antibody, wu:fi05a09 antibody, zgc:66002 antibody, guanine monophosphate synthase antibody, guanine monophosphate synthase L homeolog antibody, guanine monophosphate synthetase antibody, GMPS antibody, gmps.L antibody, gmps antibody, Gmps antibody

Background:

Synonyms: GATD7,Glutamine amidotransferase,GMP synthase [glutamine hydrolyzing],GMP synthase [glutamine-hydrolyzing],GMP synthetase,Gmps,GUAA,Guanine monophosphate synthase,Guanine monphosphate synthetase,Guanosine 5' monophosphate synthase,MLL/GMPS fusion protein,Testicular tissue protein Li 82

Background: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

Molecular Weight:

Observed_MW: 80kDa

Calculated_MW: 65kDa/76kDa

Gene ID: 8833

UniProt: P49915

Pathways: Ribonucleoside Biosynthetic Process