COQ3 antibody
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- Target See all COQ3 Antibodies
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COQ3 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human COQ3 (NP_059117.3).
- Isotype
- IgG
- Top Product
- Discover our top product COQ3 Primary Antibody
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- Application Notes
- IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
- Alternative Name
- COQ3 (COQ3 Products)
- Synonyms
- 4732433J24 antibody, C77934 antibody, DHHBMT antibody, DHHBMTASE antibody, UG0215E05 antibody, bA9819.1 antibody, ATCOQ3 antibody, EMB3002 antibody, F7F1.13 antibody, F7F1_13 antibody, coenzyme Q 3 antibody, embryo defective 3002 antibody, coenzyme Q3 methyltransferase antibody, coenzyme Q3, methyltransferase antibody, coenzyme Q 3 antibody, Coq3 antibody, COQ3 antibody
- Background
- Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
- Molecular Weight
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Observed_MW: 32kDa, 41kDa
Calculated_MW: 41kDa
- Gene ID
- 51805
- UniProt
- Q9NZJ6
- Pathways
- Methionine Biosynthetic Process
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