CD2AP antibody

Catalog No. ABIN6571364

Product Details anti-CD2AP Antibody

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD2AP antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human CD2AP

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD2AP

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Alternative Name: CD2AP (Cd2ap Products)

Synonyms: cd2apl antibody, fj51c01 antibody, im:7153970 antibody, si:ch211-207n9.1 antibody, wu:fj51c01 antibody, zgc:103705 antibody, DKFZp469E061 antibody, CMS antibody, AL024079 antibody, C78928 antibody, METS-1 antibody, Mets1 antibody, CD2-associated protein L homeolog antibody, CD2 associated protein antibody, CD2-associated protein antibody, cd2ap.L antibody, CD2AP antibody, cd2ap antibody, Cd2ap antibody

Background:

Synonyms: Adapter protein CMS,AL024079,C78928,Cas ligand with multiple SH3 domains,CD2 associated protein,CD2-associated protein,CD2AP,CD2AP,CMS,Mesenchyme to epithelium transition protein with SH3 domains 1,METS 1,Mets1

Background: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Molecular Weight:

Observed_MW: 71kDa

Calculated_MW: 71kDa

Gene ID: 23607

UniProt: Q9Y5K6