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CHRNG antibody

CHRNG Reactivity: Human, Rat, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6571431
  • Target See all CHRNG Antibodies
    CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))
    Reactivity
    • 25
    • 9
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 25
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRNG antibody is un-conjugated
    Application
    • 18
    • 13
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human CHRNG
    Isotype
    IgG
    Top Product
    Discover our top product CHRNG Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))
    Alternative Name
    CHRNG (CHRNG Products)
    Synonyms
    ACHRG antibody, Achr-3 antibody, Acrg antibody, cholinergic receptor nicotinic gamma subunit antibody, cholinergic receptor, nicotinic gamma L homeolog antibody, cholinergic receptor, nicotinic, gamma antibody, cholinergic receptor, nicotinic gamma antibody, cholinergic receptor, nicotinic, gamma polypeptide antibody, CHRNG antibody, chrng.L antibody, Chrng antibody, chrng antibody
    Background

    Synonyms: Acetylcholine receptor muscle gamma subunit,Acetylcholine receptor protein gamma chain precursor,Acetylcholine receptor subunit gamma,ACHG,ACHG,Achr 3,AChR,Achr3,ACHRG,ACRG,Cholinergic receptor nicotinic gamma ,Cholinergic receptor nicotinic gamma polypeptide,CHRNG,MGC133376

    Background: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.

    Molecular Weight

    Observed_MW: 60kDa

    Calculated_MW: 52kDa/57kDa

    Gene ID
    1146
    UniProt
    P07510
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