IL-37 antibody

Catalog No. ABIN6571621

Product Details anti-IL-37 Antibody

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-37 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human IL37

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL-37

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Alternative Name: IL37 (IL37 Products)

Synonyms: FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, interleukin 37 antibody, IL37 antibody

Background:

Synonyms: FIL1,FIL1 zeta,FIL1(ZETA),FIL1Z,IL 1 zeta,IL 1F7,IL 1F7b (IL 1H4,IL 1H,IL 1RP1),IL 1H4,IL 1RP1,IL 1X,IL 1X protein,IL-1 zeta,IL-1F7,IL-1H,IL-1H4,IL-1RP1,IL-1X,IL-37,IL1F7 (canonical product IL 1F7b),IL1F7,IL1F7,IL1H4,IL1RP1,Interleukin 1 family member 7,interleukin 1 family,member 7 (zeta),Interleukin 1 homolog 4,Interleukin 1 related protein,Interleukin 1 superfamily z,Interleukin 1 zeta,Interleukin 37,Interleukin-1 family member 7,Interleukin-1 homolog 4,Interleukin-1 zeta,Interleukin-1-related protein,Interleukin-23

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molecular Weight:

Observed_MW: 24kDa

Calculated_MW: 17kDa/19kDa/21kDa/24kDa

Gene ID: 27178

UniProt: Q9NZH6