PCDHA12 antibody
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- Target See all PCDHA12 Antibodies
- PCDHA12 (Protocadherin alpha 12 (PCDHA12))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCDHA12 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PCDHA12 (NP_114070.1).
- Isotype
- IgG
- Top Product
- Discover our top product PCDHA12 Primary Antibody
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- Application Notes
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PCDHA12 (Protocadherin alpha 12 (PCDHA12))
- Alternative Name
- PCDHA12 (PCDHA12 Products)
- Synonyms
- PCDH-ALPHA12 antibody, Pcdha11 antibody, rCNRv12 antibody, Cnr5 antibody, Crnr5 antibody, Pcdha13 antibody, CNRv12 antibody, PCDHA12 antibody, protocadherin alpha 12 antibody, protocadherin alpha-12 antibody, PCDHA12 antibody, Pcdha12 antibody, LOC102147933 antibody
- Background
- This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
- Molecular Weight
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Observed_MW: 102kDa
Calculated_MW: 85kDa/101kDa
- Gene ID
- 56137
- UniProt
- Q9UN75
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