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GLP1R antibody

GLP1R Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6571831
  • Target See all GLP1R Antibodies
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Reactivity
    • 48
    • 42
    • 26
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 54
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 57
    • 2
    Polyclonal
    Conjugate
    • 29
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLP1R antibody is un-conjugated
    Application
    • 42
    • 20
    • 19
    • 13
    • 13
    • 13
    • 11
    • 10
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human GLP1R (NP_002053.3).
    Isotype
    IgG
    Top Product
    Discover our top product GLP1R Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Alternative Name
    GLP1R (GLP1R Products)
    Synonyms
    GLP1R antibody, LOC100228311 antibody, GLP-1R antibody, GLP1Rc antibody, Glip antibody, RATGL1RCP antibody, glucagon like peptide 1 receptor antibody, glucagon-like peptide 1 receptor antibody, GLP1R antibody, Glp1r antibody
    Background
    This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
    Molecular Weight

    Observed_MW: 53kDa

    Calculated_MW: 53kDa

    Gene ID
    2740
    UniProt
    P43220
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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