TAX1BP3 antibody
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- Target See all TAX1BP3 Antibodies
- TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAX1BP3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human TAX1BP3
- Isotype
- IgG
- Top Product
- Discover our top product TAX1BP3 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
- Alternative Name
- TAX1BP3 (TAX1BP3 Products)
- Synonyms
- TIP-1 antibody, 1300011C24Rik antibody, RP23-263M10.10 antibody, tax1bp3 antibody, wu:fb37e03 antibody, wu:fc23g08 antibody, zgc:55513 antibody, Tax1 binding protein 3 antibody, Tax1 (human T cell leukemia virus type I) binding protein 3 antibody, Tax1 (human T-cell leukemia virus type I) binding protein 3 S homeolog antibody, Tax1 (human T-cell leukemia virus type I) binding protein 3 antibody, TAX1BP3 antibody, Tax1bp3 antibody, tax1bp3.S antibody, tax1bp3 antibody
- Background
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Synonyms: Glutaminase interacting protein 3,Glutaminase-interacting protein 3,Tax interaction protein 1,Tax1 (human T cell leukemia virus type I) binding protein 3,Tax1 binding protein 3,Tax1-binding protein 3,Tax1bp3,TIP 1,TIP-1,TIP1,TX1B3
Background: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways, for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
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Observed_MW: 14kDa
Calculated_MW: 13kDa
- Gene ID
- 30851
- UniProt
- O14907
- Pathways
- Monocarboxylic Acid Catabolic Process
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