NSD1 antibody
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- Target See all NSD1 Antibodies
- NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NSD1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human NSD1
- Isotype
- IgG
- Top Product
- Discover our top product NSD1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:1000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
- Alternative Name
- NSD1 (NSD1 Products)
- Synonyms
- NSD1 antibody, sto antibody, kmt3b antibody, sotos antibody, ara267 antibody, ARA267 antibody, KMT3B antibody, SOTOS antibody, SOTOS1 antibody, STO antibody, AI528500 antibody, nuclear receptor binding SET domain protein 1 antibody, histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific antibody, nuclear receptor-binding SET-domain protein 1 antibody, NSD1 antibody, nsd1 antibody, Nsd1 antibody, LOC540197 antibody
- Background
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Synonyms: Nuclear Receptor Binding SET Domain Protein 1,Nuclear Receptor-Binding SET Domain-Containing Protein 1,Androgen Receptor-Associated Protein Of 267 KDa,Androgen Receptor Coactivator 267 KDa Protein,NR-Binding SET Domain-Containing Protein,Lysine N-Methyltransferase 3B,H3-K36-HMTase,H4-K20-HMTase,EC 2.1.1.43.
Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.
- Molecular Weight
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Observed_MW: 297kDa
Calculated_MW: 267kDa/284kDa/296kDa
- Gene ID
- 64324
- UniProt
- Q96L73
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