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CD3 epsilon antibody (C-Term)

CD3E Reactivity: Human WB Host: Rabbit Polyclonal RB33593 unconjugated
Catalog No. ABIN657454
  • Target See all CD3 epsilon (CD3E) Antibodies
    CD3 epsilon (CD3E)
    Binding Specificity
    • 25
    • 20
    • 16
    • 16
    • 16
    • 14
    • 13
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 154-182, C-Term
    Reactivity
    • 217
    • 162
    • 44
    • 42
    • 18
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Host
    • 142
    • 118
    • 33
    • 22
    • 20
    • 8
    • 1
    Rabbit
    Clonality
    • 218
    • 120
    • 6
    Polyclonal
    Conjugate
    • 126
    • 31
    • 27
    • 20
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD3 epsilon antibody is un-conjugated
    Application
    • 235
    • 157
    • 86
    • 82
    • 71
    • 70
    • 27
    • 27
    • 25
    • 22
    • 14
    • 14
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Pr
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CD3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human CD3E.
    Clone
    RB33593
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CD3E Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    CD3E Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    CD3 epsilon (CD3E)
    Alternative Name
    CD3E (CD3E Products)
    Synonyms
    cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody
    Background
    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
    Molecular Weight
    23147
    Gene ID
    916
    NCBI Accession
    NP_000724
    UniProt
    P07766
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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