CD11c antibody (APC)
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- Target See all CD11c (ITGAX) Antibodies
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD11c antibody is conjugated to APC
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- Cross-Reactivity (Details)
- Cross reactivity with CD11c from other sources has not been tested
- Purification
- Allophycocyanin conjugated CD11c Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11c. Reactivity is observed against human CD11c, Baboon, Chimpanzee, Cynomolgus, and Rhesus. . Anti-CD11c is conjugated with APC under optimal conditions and the solution is free of unconjugated APC.
- Immunogen
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Immunogen: Anti-CD11c Antibody (Monoclonal) was produced by repeated immunizations with CD11c antigen.
- Clone
- 3-9
- Isotype
- IgG1
- Labeling Ratio
- 1-2
- Top Product
- Discover our top product ITGAX Primary Antibody
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- Application Notes
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Application Note: Anti-CD11c is useful for Flow Cytometry, Immunofluorescence, and Immunoprecipitation. Researchers should determine optimal titers for applications that are not stated.
Immunoprecipitation Dilution: User Optimized
Flow Cytometry Dilution: 5μL/test/1x10e5 to 1x10e8 cells
IF Microscopy Dilution: User Optimized
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
0.09 % (w/v) Sodium Azide - Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
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- Target
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
- Alternative Name
- CD11c (ITGAX Products)
- Synonyms
- CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
- Background
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Synonyms: Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150 95, CD11c
Background: The 3.9 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on activated neutrophils, granulocytes, some types of activated T cells and intestinal intraepithelial lymphocytes (IEL).L killing through its interactions with fibrinogen, CD54, and iC3b.
Gene Name: ITGAX
- Gene ID
- 3687
- NCBI Accession
- NP_000878
- UniProt
- P20702
- Pathways
- Complement System, Activated T Cell Proliferation, Integrin Complex
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