MAPT antibody

Catalog No. ABIN6657390

Supplier Product No.: 200-901-x29

This Chicken Polyclonal antibody specifically detects MAPT in WB, ELISA, IHC and FM. It exhibits reactivity toward Human.

Quick Overview for MAPT antibody (ABIN6657390)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This MAPT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Product Details anti-MAPT Antibody

Supplier Product No.: 200-901-x29

Supplier: Rockland

Purpose: TAU Antibody

Purification: Anti-Tau Antibody was purified by total IgY fraction.

Sterility: Sterile filtered

Immunogen: Anti-Tau Antibody was produced in chickens by repeated immunizations with a recombinant full length human tau expressed in and purified from E.Coli.

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:100,000

Immunohistochemistry_Dilution: 1:1,000

IF_Microscopy_Dilution: 1:1,000

Western_Blot_Dilution: 1:10,000

Other: ICC: 1:1000-1:2000

Comment:

Anti-TAU Antibody is tested for Western Blot, immunocytochemistry, immunohistochemistry, and it is specific for the ~48, 65 & 75 kDa tau isoforms. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

Expiry Date: 12 months

Target Details for MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: MAPT

Background:

Synonyms: Microtubule-associated protein tau, Neurofibrillary tangle protein, Pired helical filament-tau, PHF-tau

Background: Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons. Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing. Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer's disease (AD), Pick's disease and progressive supranuclear palsy. Tau Antibody is ideal for researchers interested in neuroscience research.

Gene Name: MAPT

Gene ID: 4137

UniProt: P10636

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size