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- Target See all Syntaxin products
- Syntaxin
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Syntaxin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Hamster, Human, Pig (Porcine), Rat (Rattus)
- Cross-Reactivity (Details)
- Cross reactivity with syntaxin from other species has not been determined.
- Purification
- Anti-Syntaxin Monoclonal Antibody is directed against Syntaxin. Syntaxin antibody was purified by Protein G chromatography. Reactivity is expected from rat, pig and hamster.
- Immunogen
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Immunogen: Anti-Syntaxin Monoclonal Antibody was produced in mouse by repeated immunizations with Synaptic immunoprecipitate (crude) from human brain.
Immunogen Type: Native Protein
- Clone
- SP8
- Isotype
- IgG1
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anti-Syntaxin antibody
Reactivity: Human, Hamster, Pig, Rat, Dog, Guinea Pig, Rabbit, Cow WB, IHC Host: Mouse Monoclonal SP6 unconjugated Recombinant Antibody
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- Application Notes
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Immunohistochemistry Dilution: 1:100
Application Note: Anti-Syntaxin antibody is suitable for use in Western Blotting and IHC. Expect a band or approximately 36 kDa in size corresponding to syntaxin proteins in Western blot of rat brain lysate. Tested for use in immunohistochemistry on formalin fixed, vibratome sections. Does not work on paraffin sections. Researchers should determine optimal titers for applications that are not stated below.
Western Blot Dilution: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- Target
- Syntaxin
- Abstract
- Syntaxin Products
- Synonyms
- CG11278 antibody, Dm Syx13 antibody, DmSyx13 antibody, Dmel\\CG11278 antibody, SYN13 antibody, Syx antibody, ff16 antibody, ff16 (69D1-70A2) antibody, l(3)01470 antibody, syx13 antibody, Tb03.5L5.810 antibody, Syntaxin 13 antibody, SYntaXin antibody, syntaxin antibody, Syx13 antibody, syx-7 antibody, Tc00.1047053508955.10 antibody, Tb927.3.5570 antibody, LOC100533375 antibody
- Background
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Synonyms: Neuron-specific antigen HPC-1, Syntaxin-1A
Background: Syntaxin antibody detects Syntaxin-1A protein which is part of a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia. Anti-Syntaxin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: STX1A
- Gene ID
- 6804
- UniProt
- Q16623
- Pathways
- Synaptic Vesicle Exocytosis
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