Adamts2 antibody (C-Term)

Catalog No. ABIN6657530

Product Details anti-Adamts2 Antibody

Target: Adamts2 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adamts2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Anti-ADAMTS2 antibody is directed against human ADAMTS2 protein.  The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on homology for the immunogen sequence.  Cross reactivity with ADAMTS2 from other sources has not been determined.

Immunogen:

Immunogen: ADAMTS2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human ADAMTS2.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry Dilution: 1:100-1:500

Application Note: Anti-ADAMTS2 is useful for Immunohistochemistry -P, -F, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~134.8 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution Volume: 100 μL

Reconstitution Buffer: Restore with deionized water (or equivalent)

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for Adamts2

Target: Adamts2 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2))

Alternative Name: ADAMTS2 (Adamts2 Products)

Synonyms: ADAM-TS2 antibody, ADAMTS-2 antibody, ADAMTS-3 antibody, PCINP antibody, hPCPNI antibody, mKIAA4060 antibody, pNPI antibody, NPI antibody, PC I-NP antibody, PCI-NP antibody, PCPNI antibody, PNPI antibody, RGD1565950 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 2 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 2 antibody, Adamts2 antibody, ADAMTS2 antibody

Background:

Synonyms: Procollagen I N-proteinase,

Background: ADAMTS2, A disintegrin and metalloproteinase with thrombospondin motifs 2, also known as procollagen I N-proteinase (PC I-NP), is an enzyme that in humans is encoded by the ADAMTS2 gene. The ADAMTS2 gene contains 22 exons. The human ADAMTS2 gene is mapped to chromosome 5q23-q24 by analysis of somatic cell hybrids. ADAMTS2 is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary for collagen molecules to function normally and assemble into fibrils outside cells. This antibody is suitable for researchers interested in signal transduction, extracellular matrix antibodies and cancer research.

Gene Name: ADAMTS2

Gene ID: 9509

NCBI Accession: NP_055059

UniProt: O95450