NR2C1 antibody (N-Term)
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- Target See all NR2C1 Antibodies
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
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Binding Specificity
- N-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR2C1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- Anti-TR2 antibody is directed against mouse Testicular Receptor 2 protein. Anti-TR2 antibody is provided as monospecific neat serum. Reactivity is expected against human and rat.
- Immunogen
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Immunogen: Anti-TR2 Antibody was produced in rabbit by repeated immunizations with TR2 fusion protein from the N-terminal region of the Testicular Receptor 2 protein.
Immunogen Type: Recombinant Protein
- Top Product
- Discover our top product NR2C1 Primary Antibody
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- Application Notes
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Application Note: Anti-Testicular Receptor 2 (Rabbit) antibody is suitable for use in Western Blots. Anti-Testicular Receptor 2 antibodies are specific for the ~64 kDa TR2 protein in Western blots of testes and nuclear extracts from MEL cell lines. Researchers should determine optimal titers for applications that are not stated below.
Western Blot Dilution: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- Target
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
- Alternative Name
- Testicular Receptor 2 (TR2) (NR2C1 Products)
- Synonyms
- TR2 antibody, NR2C1 antibody, dor2 antibody, tr2-11 antibody, xDOR2 antibody, DKFZp468M0512 antibody, si:dkey-183c16.2 antibody, zgc:110672 antibody, 4831444H07Rik antibody, 80.3 antibody, Eenr antibody, Tr2-11 antibody, Tr2 antibody, Psg4 antibody, TR2-11 antibody, PSG9 antibody, nr2c1 antibody, nuclear receptor subfamily 2 group C member 1 antibody, nuclear receptor subfamily 2 group C member 1 S homeolog antibody, nuclear receptor subfamily 2, group C, member 1 antibody, pregnancy specific beta-1-glycoprotein 4 antibody, nuclear receptor subfamily 2 group C member 1 L homeolog antibody, NR2C1 antibody, nr2c1.S antibody, nr2c1 antibody, Nr2c1 antibody, PSG4 antibody, nr2c1.L antibody
- Background
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Synonyms: Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, mTR2
Background: TR2 antibody detects Testicular receptor 2 (TR2), which is a member of the orphan nuclear receptor family. It is widely expressed at a low level throughout the adult testis. TR2 represses transcription and binds DNA directly interacting with HDAC3 and HDAC4 via DNA-binding domains. TR2 has also been implicated in regulation of estrogen receptor activity in mammary glands. In addition, TR2 has recently been shown to form a heterodimer with TR4 that can bind to the direct repeat 6 element of the hepatitis B virus (HBV) enhancer II region thus suppressing HBV gene expression. Anti-TR2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Stem Cell research.
Gene Name: NR2C1
- Gene ID
- 22025
- UniProt
- Q505F1
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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